The Board consists of nine Directors of constituent bodies, two mental health care users and six co-opted experts. The officers of the Board are the President, two Vice Presidents and an Honorary Treasurer.
President
Prof Sheila Theresa Mokoboto-Zwane
Vice President
Ms Sanja Bornman
Vice President
Dr Praveena Sukhraj-Ely
Honorary Treasurer
Mr Thomas Bertram Davies
The current members of the Board, elected in September 2020, are
| President | Prof Sheila Theresa Mokoboto-Zwane |
| Vice President | Ms Sanja Bornman |
| Vice President | Dr Praveena Sukhraj-Ely |
| Honorary Treasurer | Mr Thomas Bertram Davies |
| Board Members | Ms Karen Asia |
| Board Members | Mr Vince Boulle |
| Board Members | Dr Ingrid Elizabeth Daniels |
| Board Members | Dr Nicolas Peter Else |
| Board Members | Ms Yolande Lessing |
| Board Members | Mr Mthiyane Lungisani |
| Board Members | Mr Moses Mahlangu |
| Board Members | Mr Siphamandla Matiwane |
| Board Members | Ms Priscilla Molaudzi |
| Board Members | Ms Lucy-Ann Namukoko |
| Board Members | Ms Tilla du Preez |
| Board Members | Ms Ann Shona Playfair Sturgeon |
| Board Members | Mr Johannes Erasmus van Zyl |
| Ex Officio | Ms Bharti Patel |
