The Board consists of nine Directors of constituent bodies, two mental health care users and six co-opted experts. The officers of the Board are the President, two Vice Presidents and an Honorary Treasurer.
President
Prof Sheila Theresa Mokoboto-Zwane
Vice President
Ms Sanja Bornman
Vice President
Dr Praveena Sukhraj-Ely
Honorary Treasurer
Mr Thomas Bertram Davies
The current members of the Board, elected in September 2024, are
| President | Prof Sheila Theresa Mokoboto-Zwane |
| Vice President | Sanja Bornman |
| Vice President | Dr Praveena Sukhraj-Ely |
| Honorary Treasurer | Thomas Bertram Davies |
| Board Member | Thandeka Masilela |
| Board Member | Vince Boulle |
| Board Member | Dr Ingrid Elizabeth Daniels |
| Board Member | Emelenzia Chipo Gwaza |
| Board Member | Tshwaro Joyce Tshipo |
| Board Member | Philippa Manning |
| Board Member | Moses Mahlangu |
| Board Member | Sandra Laten |
| Board Member | Priscilla Molaudzi |
| Board Member | Kurt Pretorius |
| Board Member | Tilla du Preez |
| Board Member | Ann Shona Playfair Sturgeon |
| Board Member | Johannes Erasmus van Zyl |
| Board Member | Onthatile Tuta |
